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Human Immunodeficiency Virus Envelope Protein Gp120 Induces Proliferation but Not Apoptosis in Osteoblasts at Physiologic Concentrations

Patients with HIV infection have decreased numbers of osteoblasts, decreased bone mineral density and increased risk of fracture compared to uninfected patients; however, the molecular mechanisms behind these associations remain unclear. We questioned whether Gp120, a component of the envelope prote...

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Detalles Bibliográficos
Autores principales: Cummins, Nathan W., Klicpera, Anna, Sainski, Amy M., Bren, Gary D., Khosla, Sundeep, Westendorf, Jennifer J., Badley, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171487/
https://www.ncbi.nlm.nih.gov/pubmed/21931863
http://dx.doi.org/10.1371/journal.pone.0024876