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SiRNA targeting EGFR effectively prevents posterior capsular opacification after cataract surgery

PURPOSE: We investigated the effect of epidermal growth factor receptor (EGFR) siRNA on human lens epithelium (HLE) cells and the development of posterior capsular opacity (PCO). METHODS: We designed EGFR siRNA and used it to knockdown the expression of EGFR in HLE cells. Cell proliferation was exam...

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Detalles Bibliográficos
Autores principales: Huang, Wan-Rong, Fan, Xing-Xing, Tang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171494/
https://www.ncbi.nlm.nih.gov/pubmed/21921987