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Insights into the structure of the CCR4-NOT complex by electron microscopy

The CCR4-NOT complex is a deadenylation complex, which plays a major role for mRNA stability. The complex is conserved from yeast to human and consists of nine proteins NOT1–NOT5, CCR4, CAF1, CAF40 and CAF130. We have successfully isolated the complex using a Protein A tag on NOT1, followed by cross...

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Detalles Bibliográficos
Autores principales: Nasertorabi, Fariborz, Batisse, Claire, Diepholz, Meikel, Suck, Dietrich, Böttcher, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171648/
https://www.ncbi.nlm.nih.gov/pubmed/21669201
http://dx.doi.org/10.1016/j.febslet.2011.05.071