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Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C

Menadione (Vitamin K3) has anti-tumoral effects against a wide range of cancer cells. Its potential toxicity to normal cells and narrow therapeutic range limit its use as single agent but in combination with radiation or other anti-neoplastic agents can be of therapeutic use. In this paper, we first...

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Detalles Bibliográficos
Autores principales: Vita, Marina F., Nagachar, Nivedita, Avramidis, Dimitrios, Delwar, Zahid M., Cruz, Mabel H., Siden, Åke, Paulsson, Kajsa M., Yakisich, Juan Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171656/
https://www.ncbi.nlm.nih.gov/pubmed/20625795
http://dx.doi.org/10.1007/s10637-010-9489-0