Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

In yeast, activation of ATG1/ATG13 kinase complex initiates autophagy. This mechanism of autophagy initiation is conserved, as unc-51-like kinase 1 (ULK1) and unc-51-like kinase 2 (ULK2) are two mammalian functional homologues of ATG1 and form similar complex with mammalian ATG13. Here, we report th...

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Detalles Bibliográficos
Autores principales: Gao, W, Shen, Z, Shang, L, Wang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172118/
https://www.ncbi.nlm.nih.gov/pubmed/21475306
http://dx.doi.org/10.1038/cdd.2011.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172118/
https://www.ncbi.nlm.nih.gov/pubmed/21475306
http://dx.doi.org/10.1038/cdd.2011.33

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