Cargando…

A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination

ESCRTs (endosomal sorting complexes required for transport) bind and sequester ubiquitinated membrane proteins and usher them into multivesicular bodies (MVBs). As Ubiquitin (Ub)-binding proteins, ESCRTs themselves become ubiquitinated. However, it is unclear whether this regulates a critical aspect...

Descripción completa

Detalles Bibliográficos
Autores principales: Stringer, Daniel K., Piper, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172180/
https://www.ncbi.nlm.nih.gov/pubmed/21242292
http://dx.doi.org/10.1083/jcb.201008121