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A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
ESCRTs (endosomal sorting complexes required for transport) bind and sequester ubiquitinated membrane proteins and usher them into multivesicular bodies (MVBs). As Ubiquitin (Ub)-binding proteins, ESCRTs themselves become ubiquitinated. However, it is unclear whether this regulates a critical aspect...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Rockefeller University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172180/ https://www.ncbi.nlm.nih.gov/pubmed/21242292 http://dx.doi.org/10.1083/jcb.201008121 |