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In Vitro Evolution of Allergy Vaccine Candidates, with Maintained Structure, but Reduced B Cell and T Cell Activation Capacity

Allergy and asthma to cat (Felis domesticus) affects about 10% of the population in affluent countries. Immediate allergic symptoms are primarily mediated via IgE antibodies binding to B cell epitopes, whereas late phase inflammatory reactions are mediated via activated T cell recognition of allerge...

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Detalles Bibliográficos
Autores principales: Nilsson, Ola B., Adedoyin, Justus, Rhyner, Claudio, Neimert-Andersson, Theresa, Grundström, Jeanette, Berndt, Kurt D., Crameri, Reto, Grönlund, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172221/
https://www.ncbi.nlm.nih.gov/pubmed/21931754
http://dx.doi.org/10.1371/journal.pone.0024558