Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations

The bone marrow failure syndrome dyskeratosis congenita (DC) has been considered to be a disorder of telomere maintenance in which disease features arise due to accelerated shortening of telomeres. By screening core components of the telomerase and shelterin complexes in patients with DC and related...

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Detalles Bibliográficos
Autores principales: Vulliamy, Tom J., Kirwan, Michael J., Beswick, Richard, Hossain, Upal, Baqai, Charlotte, Ratcliffe, Anna, Marsh, Judith, Walne, Amanda, Dokal, Inderjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172236/
https://www.ncbi.nlm.nih.gov/pubmed/21931702
http://dx.doi.org/10.1371/journal.pone.0024383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172236/
https://www.ncbi.nlm.nih.gov/pubmed/21931702
http://dx.doi.org/10.1371/journal.pone.0024383

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