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Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
Endothelial cells (ECs) are the primary sensors of variations in blood oxygen concentrations. They use the hypoxia-sensitive stabilization of the hypoxia-inducible factor-1α (HIF-1α) transcription factor to engage specific transcriptional programs in response to oxygen changes. The regulation of HIF...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172262/ https://www.ncbi.nlm.nih.gov/pubmed/21775632 http://dx.doi.org/10.1091/mbc.E10-07-0617 |