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Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells

Endothelial cells (ECs) are the primary sensors of variations in blood oxygen concentrations. They use the hypoxia-sensitive stabilization of the hypoxia-inducible factor-1α (HIF-1α) transcription factor to engage specific transcriptional programs in response to oxygen changes. The regulation of HIF...

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Detalles Bibliográficos
Autores principales: Chamboredon, Sandrine, Ciais, Delphine, Desroches-Castan, Agnès, Savi, Pierre, Bono, Françoise, Feige, Jean-Jacques, Cherradi, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172262/
https://www.ncbi.nlm.nih.gov/pubmed/21775632
http://dx.doi.org/10.1091/mbc.E10-07-0617