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Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling

Anchorage dependence of cell growth, which is mediated by multiple integrin-regulated signaling pathways, is a key defense against cancer metastasis. Detachment of cells from the extracellular matrix triggers caveolin-1–dependent internalization of lipid raft components, which mediates suppression o...

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Detalles Bibliográficos
Autores principales: Norambuena, Andrés, Schwartz, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172269/
https://www.ncbi.nlm.nih.gov/pubmed/21795400
http://dx.doi.org/10.1091/mbc.E11-04-0361