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Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages

To account for the many functions of phosphatidylinositol 4,5-bisphosphate (PIP(2)), several investigators have proposed that there are separate pools of PIP(2) in the plasma membrane. Recent experiments show the surface concentration of PIP(2) is indeed enhanced in regions where phagocytosis, exocy...

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Detalles Bibliográficos
Autores principales: Golebiewska, Urszula, Kay, Jason G., Masters, Thomas, Grinstein, Sergio, Im, Wonpil, Pastor, Richard W., Scarlata, Suzanne, McLaughlin, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172273/
https://www.ncbi.nlm.nih.gov/pubmed/21795401
http://dx.doi.org/10.1091/mbc.E11-02-0114