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Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages
To account for the many functions of phosphatidylinositol 4,5-bisphosphate (PIP(2)), several investigators have proposed that there are separate pools of PIP(2) in the plasma membrane. Recent experiments show the surface concentration of PIP(2) is indeed enhanced in regions where phagocytosis, exocy...
Autores principales: | Golebiewska, Urszula, Kay, Jason G., Masters, Thomas, Grinstein, Sergio, Im, Wonpil, Pastor, Richard W., Scarlata, Suzanne, McLaughlin, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172273/ https://www.ncbi.nlm.nih.gov/pubmed/21795401 http://dx.doi.org/10.1091/mbc.E11-02-0114 |
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