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GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb

Glycogen synthase kinase 3β (GSK3β) regulates diverse physiological processes, including metabolism, development, oncogenesis, and neuroprotection. GSK3β kinase activity has been reported to be critical for various types of cancer cells, but the mechanism has remained elusive. In this study we exami...

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Detalles Bibliográficos
Autores principales: Zhou, Fangfang, Zhang, Long, van Laar, Theo, van Dam, Hans, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172276/
https://www.ncbi.nlm.nih.gov/pubmed/21795403
http://dx.doi.org/10.1091/mbc.E11-06-0483