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T Cell Epitope Regions of the P. falciparum MSP1-33 Critically Influence Immune Responses and In Vitro Efficacy of MSP1-42 Vaccines
The C-terminal 42 kDa fragments of the P. falciparum Merozoite Surface Protein 1, MSP1-42 is a leading malaria vaccine candidate. MSP1-33, the N-terminal processed fragment of MSP1-42, is rich in T cell epitopes and it is hypothesized that they enhance antibody response toward MSP1-19. Here, we gave...
Autores principales: | Pusic, Kae M., Hashimoto, Caryn N., Lehrer, Axel, Aniya, Charmaine, Clements, David E., Hui, George S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172285/ https://www.ncbi.nlm.nih.gov/pubmed/21931852 http://dx.doi.org/10.1371/journal.pone.0024782 |
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