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Identification of Hub Genes Related to the Recovery Phase of Irradiation Injury by Microarray and Integrated Gene Network Analysis

BACKGROUND: Irradiation commonly causes long-term bone marrow injury charactertized by defective HSC self-renewal and a decrease in HSC reserve. However, the effect of high-dose IR on global gene expression during bone marrow recovery remains unknown. METHODOLOGY: Microarray analysis was used to ide...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Yang, Yue, Wang, Yin, Zhang, Jinyuan, Wang, Zejian, Yin, Ming, Shen, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172286/
https://www.ncbi.nlm.nih.gov/pubmed/21931809
http://dx.doi.org/10.1371/journal.pone.0024680