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Participation of K(ATP) Channels in the Antinociceptive Effect of Pregabalin in Rat Formalin Test

BACKGROUND: Pregabalin is an anticonvulsant and analgesic agent that interacts selectively with the voltage-sensitive-Ca(2+)-channel alpha-2-delta subunit. The aim of this study was to evaluate whether the analgesic action of intrathecal (IT) pregabalin is associated with K(ATP) channels in the rat...

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Detalles Bibliográficos
Autores principales: Kweon, Tae Dong, Kim, Ji Young, Kwon, Il Won, Choi, Jong Bum, Lee, Youn Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172325/
https://www.ncbi.nlm.nih.gov/pubmed/21935490
http://dx.doi.org/10.3344/kjp.2011.24.3.131