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Inhibition of Notch signaling affects hepatic oval cell response in rat model of 2AAF-PH
BACKGROUND AND AIMS: Activation of the oval cell compartment occurs in the liver when hepatocytes are functionally compromised and/or unable to divide. Our goal was to investigate the systemic signals responsible for determining the efficiency of oval cell-mediated liver regeneration, focusing on th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172811/ https://www.ncbi.nlm.nih.gov/pubmed/21927552 http://dx.doi.org/10.2147/HMER.S12368 |