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Inhibition of Notch signaling affects hepatic oval cell response in rat model of 2AAF-PH

BACKGROUND AND AIMS: Activation of the oval cell compartment occurs in the liver when hepatocytes are functionally compromised and/or unable to divide. Our goal was to investigate the systemic signals responsible for determining the efficiency of oval cell-mediated liver regeneration, focusing on th...

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Detalles Bibliográficos
Autores principales: Darwiche, Houda, Oh, Seh-Hoon, Steiger-Luther, Nicole C, Williams, Jennifer M, Pintilie, Dana G, Shupe, Thomas D, Petersen, Bryon E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172811/
https://www.ncbi.nlm.nih.gov/pubmed/21927552
http://dx.doi.org/10.2147/HMER.S12368