In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines

BACKGROUND: Although the anti-tumour effect of cyclooxygenase-2 (Cox-2) inhibitors in invasive bladder cancer has been confirmed, its mechanisms of action are unclear. Recently, the concept of an epithelial-to-mesenchymal transition (EMT) promoting carcinoma progression has been suggested, and a key...

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Detalles Bibliográficos
Autores principales: Adhim, Z, Matsuoka, T, Bito, T, Shigemura, K, Lee, K-M, Kawabata, M, Fujisawa, M, Nibu, K, Shirakawa, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172915/
https://www.ncbi.nlm.nih.gov/pubmed/21750550
http://dx.doi.org/10.1038/bjc.2011.262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172915/
https://www.ncbi.nlm.nih.gov/pubmed/21750550
http://dx.doi.org/10.1038/bjc.2011.262

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