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In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines
BACKGROUND: Although the anti-tumour effect of cyclooxygenase-2 (Cox-2) inhibitors in invasive bladder cancer has been confirmed, its mechanisms of action are unclear. Recently, the concept of an epithelial-to-mesenchymal transition (EMT) promoting carcinoma progression has been suggested, and a key...
Autores principales: | Adhim, Z, Matsuoka, T, Bito, T, Shigemura, K, Lee, K-M, Kawabata, M, Fujisawa, M, Nibu, K, Shirakawa, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172915/ https://www.ncbi.nlm.nih.gov/pubmed/21750550 http://dx.doi.org/10.1038/bjc.2011.262 |
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