Cancer risk in patients with Noonan syndrome carrying a PTPN11 mutation

Noonan syndrome (NS) is characterized by short stature, facial dysmorphisms and congenital heart defects. PTPN11 mutations are the most common cause of NS. Patients with NS have a predisposition for leukemia and certain solid tumors. Data on the incidence of malignancies in NS are lacking. Our objec...

Descripción completa

Detalles Bibliográficos
Autores principales: Jongmans, Marjolijn C J, van der Burgt, Ineke, Hoogerbrugge, Peter M, Noordam, Kees, Yntema, Helger G, Nillesen, Willy M, Kuiper, Roland P, Ligtenberg, Marjolijn JL, van Kessel, Ad Geurts, van Krieken, J Han JM, Kiemeney, Lambertus ALM, Hoogerbrugge, Nicoline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172922/
https://www.ncbi.nlm.nih.gov/pubmed/21407260
http://dx.doi.org/10.1038/ejhg.2011.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172922/
https://www.ncbi.nlm.nih.gov/pubmed/21407260
http://dx.doi.org/10.1038/ejhg.2011.37

Ejemplares similares