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Enhanced β(2)-adrenergic receptor (β(2)AR) signaling by adeno-associated viral (AAV)-mediated gene transfer

BACKGROUND: β(2)-Adrenergic receptors (β(2)AR) play important regulatory roles in a variety of cells and organ systems and are important therapeutic targets in the treatment of airway and cardiovascular disease. Prolonged use of β-agonists results in tolerance secondary to receptor down-regulation r...

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Detalles Bibliográficos
Autores principales: Jones, Stacie M, Hiller, F Charles, Jacobi, Sandie E, Foreman, Susan K, Pittman, Laura M, Cornett, Lawrence E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317295/
https://www.ncbi.nlm.nih.gov/pubmed/14656380
http://dx.doi.org/10.1186/1471-2210-3-15