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An in vitro evaluation of guanfacine as a substrate for P-glycoprotein

BACKGROUND: With a US Food and Drug Administration-labeled indication to treat attention-deficit/hyperactivity disorder (ADHD), the nonstimulant guanfacine has become the preferred α(2)-agonist for ADHD treatment. However, significant interindividual variability has been observed in response to guan...

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Detalles Bibliográficos
Autores principales: Gillis, Nancy K, Zhu, Hao-Jie, Markowitz, John S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173033/
https://www.ncbi.nlm.nih.gov/pubmed/21931492
http://dx.doi.org/10.2147/NDT.S24153