Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation

Pathogen proteins targeting the actin cytoskeleton often serve as model systems to understand their more complex eukaryotic analogs. We show that the strong actin filament nucleation activity of Vibrio VopL depends on its three W domains and dimerization through a unique VopL C-terminal domain (VCD)...

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Detalles Bibliográficos
Autores principales: Namgoong, Suk, Boczkowska, Malgorzata, Glista, Michael J., Winkelman, Jonathan D., Rebowski, Grzegorz, Kovar, David R., Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173040/
https://www.ncbi.nlm.nih.gov/pubmed/21873985
http://dx.doi.org/10.1038/nsmb.2109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173040/
https://www.ncbi.nlm.nih.gov/pubmed/21873985
http://dx.doi.org/10.1038/nsmb.2109

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