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Hepatitis C Virus (HCV) Envelope Glycoproteins E1 and E2 Contain Reduced Cysteine Residues Essential for Virus Entry

The HCV envelope glycoproteins E1 and E2 contain eight and 18 highly conserved cysteine residues, respectively. Here, we examined the oxidation state of E1E2 heterodimers incorporated into retroviral pseudotyped particles (HCVpp) and investigated the significance of free sulfhydryl groups in cell cu...

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Detalles Bibliográficos
Autores principales: Fraser, Johanna, Boo, Irene, Poumbourios, Pantelis, Drummer, Heidi E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173156/
https://www.ncbi.nlm.nih.gov/pubmed/21768113
http://dx.doi.org/10.1074/jbc.M111.269605