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Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA) by Decreasing Mitochondrial ATP Production

The uncoupling proteins UCP2 and UCP3 have been postulated to catalyze Ca(2+) entry across the inner membrane of mitochondria, but this proposal is disputed, and other, unrelated proteins have since been identified as the mitochondrial Ca(2+) uniporter. To clarify the role of UCPs in mitochondrial C...

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Detalles Bibliográficos
Autores principales: De Marchi, Umberto, Castelbou, Cyril, Demaurex, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173197/
https://www.ncbi.nlm.nih.gov/pubmed/21775425
http://dx.doi.org/10.1074/jbc.M110.216044