Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

The protein ABIN1 possesses a polyubiquitin-binding domain homologous to that present in nuclear factor κB (NF-κB) essential modulator (NEMO), a component of the inhibitor of NF-κB (IκB) kinase (IKK) complex. To address the physiological significance of polyubiquitin binding, we generated knockin mi...

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Detalles Bibliográficos
Autores principales: Nanda, Sambit K., Venigalla, Ram K.C., Ordureau, Alban, Patterson-Kane, Janet C., Powell, David W., Toth, Rachel, C. Arthur, J. Simon, Cohen, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173241/
https://www.ncbi.nlm.nih.gov/pubmed/21606507
http://dx.doi.org/10.1084/jem.20102177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173241/
https://www.ncbi.nlm.nih.gov/pubmed/21606507
http://dx.doi.org/10.1084/jem.20102177

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