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Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

The aorta-gonad-mesonephros region plays an important role in hematopoietic stem cell (HSC) development during mouse embryogenesis. The vascular endothelial cadherin(+) CD45(+) (VE-cad(+)CD45(+)) population contains the major type of immature pre-HSCs capable of developing into long-term repopulatin...

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Detalles Bibliográficos
Autores principales: Rybtsov, Stanislav, Sobiesiak, Malgorzata, Taoudi, Samir, Souilhol, Céline, Senserrich, Jordi, Liakhovitskaia, Anna, Ivanovs, Andrejs, Frampton, Jon, Zhao, Suling, Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173253/
https://www.ncbi.nlm.nih.gov/pubmed/21624936
http://dx.doi.org/10.1084/jem.20102419