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Biochemical characterization of trans-sialidase TS1 variants from Trypanosoma congolense

BACKGROUND: Animal African trypanosomiasis, sleeping sickness in humans and Nagana in cattle, is a resurgent disease in Africa caused by Trypanosoma parasites. Trans-sialidases expressed by trypanosomes play an important role in the infection cycle of insects and mammals. Whereas trans-sialidases of...

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Detalles Bibliográficos
Autores principales: Koliwer-Brandl, Hendrik, Gbem, Thaddeus T, Waespy, Mario, Reichert, Olga, Mandel, Philipp, Drebitz, Eric, Dietz, Frank, Kelm, Sørge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173295/
https://www.ncbi.nlm.nih.gov/pubmed/21801439
http://dx.doi.org/10.1186/1471-2091-12-39