Cargando…
Human Ovarian Tumor Cells Escape γδ T Cell Recognition Partly by Down Regulating Surface Expression of MICA and Limiting Cell Cycle Related Molecules
BACKGROUND: Mechanisms of human Vγ2Vδ2 T cell-mediated tumor immunity have yet to be fully elucidated. METHODS AND FINDINGS: At least some tumor cell recognition is mediated by NKG2D-MICA interactions. Herein, by using MTT assay and PI-BrdU co-staining and Western-blot, we show that these Vγ2Vδ2 T c...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173356/ https://www.ncbi.nlm.nih.gov/pubmed/21935360 http://dx.doi.org/10.1371/journal.pone.0023348 |