Phosphatidylinositol 3'-kinase, mTOR, and Glycogen synthase kinase-3β mediated regulation of p21 in human urothelial carcinoma cells

BACKGROUND: The PTEN/Phosphatidylinositol 3'-kinase (PI3-kinase) growth factor signaling pathway plays a critical role in epithelial tumor development in a multitude of tissue types. Deletion of the Pten tumor suppressor gene in murine urothelial cells in vivo results in upregulation of cyclin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Yohn, Nicole L, Bingaman, Caitlyn N, DuMont, Ashley L, Yoo, Lina I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173386/
https://www.ncbi.nlm.nih.gov/pubmed/21864408
http://dx.doi.org/10.1186/1471-2490-11-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173386/
https://www.ncbi.nlm.nih.gov/pubmed/21864408
http://dx.doi.org/10.1186/1471-2490-11-19

Ejemplares similares