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MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1

BACKGROUND: Epithelial-mesenchymal transition (EMT) is the key process driving cancer metastasis. Oncogene/self renewal factor BMI-1 has been shown to induce EMT in cancer cells. Recent studies have implied that noncoding microRNAs (miRNAs) act as crucial modulators for EMT. The aims of this study w...

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Detalles Bibliográficos
Autores principales: Dong, Peixin, Kaneuchi, Masanori, Watari, Hidemichi, Hamada, Junichi, Sudo, Satoko, Ju, Jingfang, Sakuragi, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173388/
https://www.ncbi.nlm.nih.gov/pubmed/21851624
http://dx.doi.org/10.1186/1476-4598-10-99