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Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death

BACKGROUND: Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular al...

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Detalles Bibliográficos
Autores principales: Tare, Meghana, Modi, Rohan M., Nainaparampil, Jaison J., Puli, Oorvashi Roy, Bedi, Shimpi, Fernandez-Funez, Pedro, Kango-Singh, Madhuri, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173392/
https://www.ncbi.nlm.nih.gov/pubmed/21949710
http://dx.doi.org/10.1371/journal.pone.0024361