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Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death
BACKGROUND: Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular al...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173392/ https://www.ncbi.nlm.nih.gov/pubmed/21949710 http://dx.doi.org/10.1371/journal.pone.0024361 |