Cargando…
Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death
BACKGROUND: Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular al...
Autores principales: | Tare, Meghana, Modi, Rohan M., Nainaparampil, Jaison J., Puli, Oorvashi Roy, Bedi, Shimpi, Fernandez-Funez, Pedro, Kango-Singh, Madhuri, Singh, Amit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173392/ https://www.ncbi.nlm.nih.gov/pubmed/21949710 http://dx.doi.org/10.1371/journal.pone.0024361 |
Ejemplares similares
-
Novel Neuroprotective Function of Apical-Basal Polarity Gene Crumbs in Amyloid Beta 42 (Aβ42) Mediated Neurodegeneration
por: Steffensmeier, Andrew M., et al.
Publicado: (2013) -
Cullin-4 regulates Wingless and JNK signaling-mediated cell death in the Drosophila eye
por: Tare, Meghana, et al.
Publicado: (2016) -
A Positive Feedback Loop of Hippo- and c-Jun-Amino-Terminal Kinase Signaling Pathways Regulates Amyloid-Beta-Mediated Neurodegeneration
por: Irwin, Madison, et al.
Publicado: (2020) -
Homeotic Gene teashirt (tsh) Has a Neuroprotective Function in Amyloid-Beta 42 Mediated Neurodegeneration
por: Moran, Michael T., et al.
Publicado: (2013) -
Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer’s Disease
por: Cutler, Timothy, et al.
Publicado: (2015)