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Association between the Interleukin-6 Promoter Polymorphism −174G/C and Serum Lipoprotein(a) Concentrations in Humans

BACKGROUND: Lipoprotein(a) [Lp(a)] is an independent risk factor for cardiovascular disease. The interleukin-6 (IL-6) receptor antagonist tocilizumab has been shown to lower serum Lp(a) concentrations. We investigated whether the IL-6 single nucleotide polymorphism −174G/C is associated with baselin...

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Detalles Bibliográficos
Autores principales: Berthold, Heiner K., Laudes, Matthias, Krone, Wilhelm, Gouni-Berthold, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173458/
https://www.ncbi.nlm.nih.gov/pubmed/21935443
http://dx.doi.org/10.1371/journal.pone.0024719