Discovery of Dual-Action Membrane-Anchored Modulators of Incretin Receptors

BACKGROUND: The glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1) receptors are considered complementary therapeutic targets for type 2 diabetes. Using recombinant membrane-tethered ligand (MTL) technology, the present study focused on defining optimized modu...

Descripción completa

Detalles Bibliográficos
Autores principales: Fortin, Jean-Philippe, Chinnapen, Daniel, Beinborn, Martin, Lencer, Wayne, Kopin, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173463/
https://www.ncbi.nlm.nih.gov/pubmed/21935440
http://dx.doi.org/10.1371/journal.pone.0024693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173463/
https://www.ncbi.nlm.nih.gov/pubmed/21935440
http://dx.doi.org/10.1371/journal.pone.0024693

Ejemplares similares