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Unusual Loop-Sequence Flexibility of the Proximal RNA Replication Element in EMCV

Picornaviruses contain stable RNA structures at the 5′ and 3′ ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5′ end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that functioning of...

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Detalles Bibliográficos
Autores principales: Zoll, Jan, Hahn, Marc M., Gielen, Paul, Heus, Hans A., Melchers, Willem J. G., van Kuppeveld, Frank J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173479/
https://www.ncbi.nlm.nih.gov/pubmed/21935472
http://dx.doi.org/10.1371/journal.pone.0024818