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Unusual Loop-Sequence Flexibility of the Proximal RNA Replication Element in EMCV
Picornaviruses contain stable RNA structures at the 5′ and 3′ ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5′ end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that functioning of...
Autores principales: | Zoll, Jan, Hahn, Marc M., Gielen, Paul, Heus, Hans A., Melchers, Willem J. G., van Kuppeveld, Frank J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173479/ https://www.ncbi.nlm.nih.gov/pubmed/21935472 http://dx.doi.org/10.1371/journal.pone.0024818 |
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