Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study

INTRODUCTION: Dapagliflozin is a first-in-class sodium-glucose transporter 2 (SGLT2) inhibitor under investigation for the treatment of type 2 diabetes mellitus. A thorough QTc study was conducted, according to International Conference on Harmonization E14 guidelines, to characterize the effect of d...

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Detalles Bibliográficos
Autores principales: Carlson, Glenn F., Tou, Conrad K. P., Parikh, Shamik, Birmingham, Bruce K., Butler, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare Communications 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173598/
https://www.ncbi.nlm.nih.gov/pubmed/22127822
http://dx.doi.org/10.1007/s13300-011-0003-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173598/
https://www.ncbi.nlm.nih.gov/pubmed/22127822
http://dx.doi.org/10.1007/s13300-011-0003-2

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