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Biophysical and Computational Studies of Membrane Penetration by the GRP1 Pleckstrin Homology Domain

The pleckstrin homology (PH) domain of the general receptor for phosphoinositides 1 (GRP1) exhibits specific, high-affinity, reversible binding to phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P(3)) at the plasma membrane, but the nature and extent of the interaction between this bound comple...

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Detalles Bibliográficos
Autores principales: Lumb, Craig N., He, Ju, Xue, Yi, Stansfeld, Phillip J., Stahelin, Robert V., Kutateladze, Tatiana G., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173609/
https://www.ncbi.nlm.nih.gov/pubmed/21893292
http://dx.doi.org/10.1016/j.str.2011.04.010