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Lipopolysaccharide Inhibits the Channel Activity of the P2X7 Receptor

The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) is one of the strongest stimuli of the immune response, and it has been shown t...

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Detalles Bibliográficos
Autores principales: Leiva-Salcedo, Elias, Coddou, Claudio, Rodríguez, Felipe E., Penna, Antonello, Lopez, Ximena, Neira, Tanya, Fernández, Ricardo, Imarai, Mónica, Rios, Miguel, Escobar, Jorge, Montoya, Margarita, Huidobro-Toro, J. Pablo, Escobar, Alejandro, Acuña-Castillo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173735/
https://www.ncbi.nlm.nih.gov/pubmed/21941410
http://dx.doi.org/10.1155/2011/152625