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The tumor suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements

In Drosophila, defects in asymmetric cell division often result in the formation of stem cell derived tumors. Here, we show that very similar terminal brain tumor phenotypes arise through a fundamentally different mechanism. We demonstrate that brain tumors in l(3)mbt mutants originate from overprol...

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Detalles Bibliográficos
Autores principales: Richter, Constance, Oktaba, Katarzyna, Steinmann, Jonas, Müller, Jürg, Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173870/
https://www.ncbi.nlm.nih.gov/pubmed/21857667
http://dx.doi.org/10.1038/ncb2306