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The tumor suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements
In Drosophila, defects in asymmetric cell division often result in the formation of stem cell derived tumors. Here, we show that very similar terminal brain tumor phenotypes arise through a fundamentally different mechanism. We demonstrate that brain tumors in l(3)mbt mutants originate from overprol...
Autores principales: | Richter, Constance, Oktaba, Katarzyna, Steinmann, Jonas, Müller, Jürg, Knoblich, Juergen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173870/ https://www.ncbi.nlm.nih.gov/pubmed/21857667 http://dx.doi.org/10.1038/ncb2306 |
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