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Homology modeling of human serum paraoxonase1 and its molecular interaction studies with aspirin and cefazolin

Human serum paraoxonase1 (HuPON1) belongs to the family of A-esterases (EC.3.1.8.1). It is associated with HDL particle and prevents atherosclerosis by cleaving lipid hydroperoxides and other proatherogenic molecules of oxidized low density lipoproteins (LDL). Since the precise structure of HuPON1 i...

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Detalles Bibliográficos
Autores principales: Salman, Mohammed, Malleda, Chandramouli, Suneel, Narayanavari A, Qureshi, Insaf A, Frank, Elizabeth A, D’Souza, Cletus JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174037/
https://www.ncbi.nlm.nih.gov/pubmed/21938206