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Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates

Suppression of lipolysis by acipimox is known to improve insulin-stimulated glucose disposal, and this is an important phenomenon. The mechanism has been assumed to be an enhancement of glucose storage as glycogen, but no direct measurement has tested this concept or its possible relationship to the...

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Detalles Bibliográficos
Autores principales: Lim, Ee L., Hollingsworth, Kieren G., Smith, Fiona E., Thelwall, Peter E., Taylor, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174053/
https://www.ncbi.nlm.nih.gov/pubmed/21388348
http://dx.doi.org/10.1042/CS20100611