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Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions

Anaemia and RBC (red blood cell) transfusion may be associated with worse clinical outcomes, especially with longer blood storage duration prior to transfusion. The mechanisms underlying these harmful effects are unknown. RBCs have been proposed to buffer plasma S1P (sphingosine 1-phosphate), a lyso...

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Detalles Bibliográficos
Autores principales: Selim, Samy, Sunkara, Manjula, Salous, Abdelghaffar K., Leung, Steve W., Berdyshev, Evgeny V., Bailey, Alison, Campbell, Charles L., Charnigo, Richard, Morris, Andrew J., Smyth, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174054/
https://www.ncbi.nlm.nih.gov/pubmed/21749329
http://dx.doi.org/10.1042/CS20110236