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Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions
Anaemia and RBC (red blood cell) transfusion may be associated with worse clinical outcomes, especially with longer blood storage duration prior to transfusion. The mechanisms underlying these harmful effects are unknown. RBCs have been proposed to buffer plasma S1P (sphingosine 1-phosphate), a lyso...
Autores principales: | Selim, Samy, Sunkara, Manjula, Salous, Abdelghaffar K., Leung, Steve W., Berdyshev, Evgeny V., Bailey, Alison, Campbell, Charles L., Charnigo, Richard, Morris, Andrew J., Smyth, Susan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174054/ https://www.ncbi.nlm.nih.gov/pubmed/21749329 http://dx.doi.org/10.1042/CS20110236 |
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