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Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL

The SOUL protein is known to induce apoptosis by provoking the mitochondrial permeability transition, and a sequence homologous with the BH3 (Bcl-2 homology 3) domains has recently been identified in the protein, thus making it a potential new member of the BH3-only protein family. In the present st...

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Detalles Bibliográficos
Autores principales: Ambrosi, Emmanuele, Capaldi, Stefano, Bovi, Michele, Saccomani, Gianmaria, Perduca, Massimiliano, Monaco, Hugo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174058/
https://www.ncbi.nlm.nih.gov/pubmed/21639858
http://dx.doi.org/10.1042/BJ20110257