Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene

BACKGROUND: Random monoallelic expression contributes to phenotypic variation of cells and organisms. However, the epigenetic mechanisms by which individual alleles are randomly selected for expression are not known. Taking cues from chromatin signatures at imprinted gene loci such as the insulin-li...

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Detalles Bibliográficos
Autores principales: Thomas, Brandon J, Rubio, Eric D, Krumm, Niklas, Broin, Pilib Ó, Bomsztyk, Karol, Welcsh, Piri, Greally, John M, Golden, Aaron A, Krumm, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174113/
https://www.ncbi.nlm.nih.gov/pubmed/21812971
http://dx.doi.org/10.1186/1756-8935-4-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174113/
https://www.ncbi.nlm.nih.gov/pubmed/21812971
http://dx.doi.org/10.1186/1756-8935-4-14

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