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IL-18 Inhibits Growth of Murine Orthotopic Prostate Carcinomas via Both Adaptive and Innate Immune Mechanisms

Interleukin(IL)-18 is a pleiotrophic cytokine with functions in immune modulation, angiogenesis and bone metabolism. In this study, the potential of IL-18 as an immunotherapy for prostate cancer (PCa) was examined using the murine model of prostate carcinoma, RM1 and a bone metastatic variant RM1(BM...

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Detalles Bibliográficos
Autores principales: Tse, Brian Wan-Chi, Russell, Pamela Joan, Lochner, Matthias, Förster, Irmgard, Power, Carl Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174151/
https://www.ncbi.nlm.nih.gov/pubmed/21935389
http://dx.doi.org/10.1371/journal.pone.0024241