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IL-18 Inhibits Growth of Murine Orthotopic Prostate Carcinomas via Both Adaptive and Innate Immune Mechanisms

Interleukin(IL)-18 is a pleiotrophic cytokine with functions in immune modulation, angiogenesis and bone metabolism. In this study, the potential of IL-18 as an immunotherapy for prostate cancer (PCa) was examined using the murine model of prostate carcinoma, RM1 and a bone metastatic variant RM1(BM...

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Detalles Bibliográficos
Autores principales:	Tse, Brian Wan-Chi, Russell, Pamela Joan, Lochner, Matthias, Förster, Irmgard, Power, Carl Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174151/ https://www.ncbi.nlm.nih.gov/pubmed/21935389 http://dx.doi.org/10.1371/journal.pone.0024241

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